Roles of kallikrein-kinin system in vascular smooth muscle cell proliferation and migration
10.3760/cma.j.issn.1673-4165.2012.07.014
- VernacularTitle:激肽释放酶-激肽系统在血管平滑肌细胞增殖和迁移中的作用
- Author:
Liang GE
;
Ling LIU
;
Fang YANG
;
Renliang ZHANG
- Publication Type:Journal Article
- Keywords:
Kallikrein-Kinin System;
Muscle,Smooth,Vascular;
Myocytes,Smooth Muscle;
Cell Proliferation;
Cell Movement;
Atherosclerosis;
Angioplasty,Balloon
- From:
International Journal of Cerebrovascular Diseases
2012;20(7):551-554
- CountryChina
- Language:Chinese
-
Abstract:
Vascular smooth muscle cell (VSMC) proliferation and migation play important roles in the occurrence and development of atherosclerosis and restenosis after intravascular stenting.The studies in recent years have shown that kallikrein-kinin system (KKS) is closely correlated with VSMC proliferation and migration in cytokines and transduction pathways.Therefore,investigating the roles of KKS in the VSMC proliferation and migation process has great significance in clinical prevention and treatment of atherosclerosis and restenosis after intravascular stenting.
