The cognitive changes in patients with lacunar infarction after antery-intervention therapy
10.3760/cma.j.issn.1674-6554.2012.07.001
- VernacularTitle:腔隙性脑梗死患者介入治疗术后认知功能变化
- Author:
Xiuqin ZHAO
;
Bing ZHAO
;
Zhangyong XIA
;
Hua YANG
;
Fenge ZHANG
;
Cunju GUO
;
Huaiqian QU
- Publication Type:Journal Article
- Keywords:
Lacunar infarction;
Carotid stenosis;
Antery-intervention therapy;
Cognition disorders
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2012;21(7):577-579
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the characteristics of the cognitive changes in patients with lacunar infarction(LI) after carotid artery stenting(CAS).MethodsNeuropsychological tests were conducted in 43 patients with LI and carotid stenosis before and 1 month,6 months,12 months after CAS and the scores were compared with those of 41 healthy cases.ResultsCompared with control group,MMSE scores ( 26.33 ± 1.94),memory and executive function in therapy group lowered obviously.There was statistical difference (P< 0.05 or P< 0.01 ).Compared with before CAS,MMSE scores of 1 month (27.17±2.15),6 months (27.17 ±2.15),12 months (28.15±1.98) after CAS,memory and executive function in therapy group were all better obviously.There was statistical difference (P<0.05 or P<0.01).ConclusionIn acute stage of patients with LI (with in 1 week),most cognitive impairment was severe. Most cognition disorders was improved to normal level 12 months after CAS.The mechanism may be associated with the improvement of chronic cerebral insufficiency.