The cognitive changes in patients with lacunar infarction after antery-intervention therapy

VernacularTitle:腔隙性脑梗死患者介入治疗术后认知功能变化
Author: Xiuqin ZHAO ; Bing ZHAO ; Zhangyong XIA ; Hua YANG ; Fenge ZHANG ; Cunju GUO ; Huaiqian QU
Publication Type:Journal Article
Keywords: Lacunar infarction; Carotid stenosis; Antery-intervention therapy; Cognition disorders
From: Chinese Journal of Behavioral Medicine and Brain Science 2012;21(7):577-579
CountryChina
Language:Chinese
Abstract: ObjectiveTo explore the characteristics of the cognitive changes in patients with lacunar infarction(LI) after carotid artery stenting(CAS).MethodsNeuropsychological tests were conducted in 43 patients with LI and carotid stenosis before and 1 month,6 months,12 months after CAS and the scores were compared with those of 41 healthy cases.ResultsCompared with control group,MMSE scores ( 26.33 ± 1.94),memory and executive function in therapy group lowered obviously.There was statistical difference (P＜ 0.05 or P＜ 0.01 ).Compared with before CAS,MMSE scores of 1 month (27.17±2.15),6 months (27.17 ±2.15),12 months (28.15±1.98) after CAS,memory and executive function in therapy group were all better obviously.There was statistical difference (P＜0.05 or P＜0.01).ConclusionIn acute stage of patients with LI (with in 1 week),most cognitive impairment was severe. Most cognition disorders was improved to normal level 12 months after CAS.The mechanism may be associated with the improvement of chronic cerebral insufficiency.