Effect of swimming training on the motor behavior and expression of BDNF and trkB in adrenal body

VernacularTitle:游泳训练对大鼠运动行为和肾上腺脑源性神经营养因子和trkB表达的影响
Author: Yuan YUAN ; Hangping WANG ; Xiaoming ZHAO ; Dawei LI ; Hua LIU ; Juan LIU ; Zhenwu SUN ; Longhui ZHOU ; Qiqin DAN ; Tinghua WANG
Publication Type:Journal Article
Keywords: Rat; Swimming; Adrenal body; Brain derived neurotrophic factor; trkB
From: Chinese Journal of Behavioral Medicine and Brain Science 2012;21(7):638-640
CountryChina
Language:Chinese
Abstract: ObjectiveTo explore the effect of swimming on motor behavior and expression of brain derived neurotrophic factor(BDNF) and trkB in adrenal body.MethodsSD adult rats were divided into normal cotrol group and swimming group ( n=10 in each group).All rats in swimming group were subjected 6 weeks swimming for 1h each day.Motor performances including swimming speed and distance were recorded and expression of BDNF and trkB in adrenal body was measured.ResultsThere was a significant increase in swimming speed ( ( 157 ± 60) m/min) and distance ( (283.36 ±49.50)m) in swimming group,compared with control group ( (283± 60) m/min,( 156.92 ± 29) m) (P ＜ 0.05 ).Simultaneously,expression of BDNF in adrenal body had been significantly unregulated (0.93 ± 0.09 vs 0.56 ± 0.19 ) (P ＜ 0.05 ),while expression of trkB kept to be not changed.ConclusionSwimming increases notor ability in rats,and the possible mechanism may be related the upregulation of BDNF in adrenal body.