NADPH oxidase and cerebral ischemia-reperfusion injury
10.3760/cma.j.issn.1673-4165.2012.06.015
- VernacularTitle:NADPH氧化酶与脑缺血再灌注损伤
- Author:
Li ZHANG
;
Ketan CHU
;
Benyan LUO
- Publication Type:Journal Article
- Keywords:
NADPH Oxidase;
Superoxides;
Reactive Oxygen Species;
Brain Ischemia;
Reperfusion Injury
- From:
International Journal of Cerebrovascular Diseases
2012;20(6):465-467
- CountryChina
- Language:Chinese
-
Abstract:
NADPH oxidases are a family of multi-subunit enzyme eomplexes.It catalyzes the production of reactive oxygen species (ROS).A large number of studies have shown that oxidative stress plays a very important role in cerebral ischemia-reperfusion injury,and the find of the expression changes about NADPH oxidase after cerebral ischemia may provide a new idea for the prevention and treatment of ischemic stroke.NADPH oxidase may become a new therapeutic target.
