The clinical study on the risk of permanent hair dye use for connective tissue disease with positive antinuclear antibodies
10.3760/cma.j.issn.1007-7480.2012.06.004
- VernacularTitle:永久性染发剂与抗核抗体阳性结缔组织病发病风险的临床研究
- Author:
Yufang GONG
;
Qiaofeng WEI
;
Xiuhua WANG
;
Ming LV
;
Xingfu LI
- Publication Type:Journal Article
- Keywords:
Hair dyes;
Connective tissue diseases;
Lupus erythematosus,systemic
- From:
Chinese Journal of Rheumatology
2012;16(6):375-378
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk of permanent hair dye use for connective tissue disease ( CTD ) with positive antinuclear antibodies ( ANA ).Methods We conducted a population-based case-control study to analyze 440 CTD patients from the department of our hospital.Four hundreds and forty patients' relatives or friends who were free from any CTD were selected as controls.Patients and controls were matched in sex and age.A face-to-face interview was adopted to finish questionnaires about subjects' demographic data and the use of permanent hair dye.Data about the duration,frequency,times of usage and allergy related to hair dye were collected.Medical history was also reviewed,such as the diagnosis,disease course,primary symptoms,serum tests and organ involvements.Statistical analysis was performed by SPSS 17.0 software using x2 test and Logistic regression.Results The association between the use of permanent hair dye and CTD did not reach statistical significance (OR=1.282,95％CI 0.966-1.700,P=0.085 ),when the relationship of hair dye use with systemic lupus erythematosus (SLE) was tested,the same result (OR=1.092,95％CI 0.795-1.500,P=0.587 ) could be revealed.Conclusion This preliminary study has shown that the use of permanent hair dye couldn't induce the occurrence of CTD.
