Clinical characteristics of 54 cases with Sheehan's syndrome

VernacularTitle:54例希恩综合征患者临床特征分析及文献复习
Author: Yayi HE ; Miao WEI ; Bingyin SHI
Publication Type:Journal Article
Keywords: Sheehan's syndrome; Crisis; Glucocorticoid
From: Chinese Journal of Endocrinology and Metabolism 2012;28(7):557-560
CountryChina
Language:Chinese
Abstract: Medical histories and clinical data of 54 patients with Sheehan's syndrome (SS) in endocrine department from August 2008 to August 2011 were collected and analyzed retrospectively.47 cases of SS were accompanied by pituitary crisis.19 cases had been misdiagnosed previously.The average period from the obstetric events to diagnosis of SS was ( 12.36 ± 1.28 ) years.Intravenous drip of hydrocortisone was given for rescuing pituitary crisis.The average dosages of hydrocortisone for the first 24 hours and the second 24 hours were ( 83.93 ± 7.73 ) and (42.19 ± 5.13 ) mg respectively. 12 cases of SS presented transient psychosis after the regular dosage of oral glucocorticoid replacement.