Effects of pioglitazone on the expression of adipose triglyceride lipase in obese rats
10.3760/cma.j.issn.1000-6699.2012.06.018
- VernacularTitle:吡格列酮对肥胖大鼠脂肪甘油三酯脂酶表达的调控
- Author:
Chuaoyu ZHU
;
Xiaohua LIU
;
Jianmei ZHANG
;
Miao XU
;
Li WEI
;
Weiping JIA
- Publication Type:Journal Article
- Keywords:
Adipose triglyceride lipase;
Insulin resistance;
Pioglitazone
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(6):509-511
- CountryChina
- Language:Chinese
-
Abstract:
To detect the effects of pioglitazone on adipose triglyceride lipase (ATGL) in adipose,liver,and muscle of high-fat diet-induced obese rats.Insulin resistance aud decreased expression of adipose triglyceride lipase were found in the adipose,liver,and muscle tissues.Pioglitazone may improve insulin sensitivity and ameliorate ATGL expression in tissues of high-fat diet-induced obese rats.
