Location of brain areas in which pain is induced by mechanical noxious stimulation: a functional magnetic resonance imaging study

VernacularTitle:机械性伤害性刺激诱发疼痛的脑区定位:功能性磁共振成像研究
Author: Hongyu TAN ; Sifang LIN ; Xiang QUAN ; Tiehu YE
Publication Type:Journal Article
Keywords: Physical stimulation; Pain; Magnetic resonance imaging; Brain
From: Chinese Journal of Anesthesiology 2012;32(7):784-786
CountryChina
Language:Chinese
Abstract: Objective To locate the brain areas in which pain was induced by mechanical noxious stimulation by using functional magnetic resonance imaging.Methods Twenty healthy male volunteers,aged 20-40 yr,with body mass index of 18-25 kg/m2,were involved in this study.The volunteers were stimulated with 300 g von Frey filaments.Functional magnetic resonance imaging examinations were performed 1 week later.The monitoring data were collected during the scanning.The images were analyzed with SPM2 software.Results Bain areas in which pain was induced by mechanical noxious stimulation with 300 g yon Frey filaments were bilateral anterior cingulate gyrus,right contralateral insula and bilateral primary somatic sensory cortex.Conclusion The brain areas in which pain is induced by mechanical noxious stimulation include bilateral anterior cingulate gyrus,right contralateral insula and bilateral primary somatic sensory cortex.