The application value of diffusion-weighted magnetic resonance imaging in gross tumor volume delineation of esophageal squamous cell carcinoma
10.3760/cma.j.issn.1004-4221.2012.04.016
- VernacularTitle:磁共振弥散加权成像在食管癌大体肿瘤靶区勾画中的应用价值
- Author:
Dongliang HOU
;
Gaofeng SHI
;
Xianshu GAO
;
Xueying LI
;
Hui LIU
;
Yaning WANG
;
Yuekao LI
;
Qi WANG
;
Junfeng LIU
;
Qingyi LIU
;
Yueping LIU
;
Chen YAO
;
Zhiguo ZHOU
;
Xueying QIAO
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Diffusion-weighted magnetic resonance imaging;
Target delineation
- From:
Chinese Journal of Radiation Oncology
2012;21(4):343-347
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo analyze the application value of diffusion-weighted magnetic resonance imaging (DWMRI) in gross tumor volume (GTV) delineation of esophageal squamous cell carcinoma (SCC).MethodsTwenty-nine patients with esophageal SCC treated with radical surgery were analyzed.Routine CT scan,MRI T2-weighted and DWMRI were employed before surgery;diffusion-sensitive gradient b-values were taken 400,600 and 800 s/mm2.GTVs were delineated using CT,MRI T2-weighted images and DWMRI under different b-value images.The length of GTVs measured under different images was compared with the pathological length and confirm the most accurate imaging condition.Use radiotherapy planning system to fuse DWMRI images and CT images to investigate the possibility of delineate GTVs on fused images.ResultsThe difference of GTV length value between CT,T2 WI images and specimen was 3.36 mm and 2.84 mm.When b =400,600 and 800 s/mm2,the difference between GTV length value on the DWMRI images and on specimen was 0.47 mm,-0.47 mm and - 1.53 mm;the correlation coefficient of the measuring esophageal lengths on DWMRI images and the pathological lengths was 0.928,0.927 and 0.938.DWMRI images and CT images could fuse accurately on radiotherapy planning system.GTV margin could.show clearly on fused images.ConclusionsDWMRI images can display the esophageal carcinoma lengths and margin accurately.When DWMRI images fused with CT images,GTV margin could show clearly,it can be used to delineate GTV accurately.
