Investigation of attentional bias to word-related cues in male alcohol dependent patients
10.3760/cma.j.issn.1674-6554.2012.06.014
- VernacularTitle:男性酒依赖患者戒酒初期对汉字线索注意偏向相关研究
- Author:
Liangjun PANG
;
Liangshuang YIN
;
Chunyan ZHU
;
Yongmei WANG
;
Wenwen DONG
;
Jing DAI
;
Qi YANG
;
Gangqiang SUN
;
Bao HUANG
- Publication Type:Journal Article
- Keywords:
Alcohol dependent;
Attentional bias;
Stroop task
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2012;21(6):524-526
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the attentional biases in male alcohol dependent (AD) patients and the correlations between the attentional bias and alcohol-related factors.MethodsA total of 30 recently detoxified male individuals with alcoholism were compared with 37 healthy controls ( HC ) on the Chinese Emotional Stroop Task using negative,neutral,and alcohol-related words.ResultsThe comparison between AD group( ( 1382.13 ±323.38) ms,( 1365.76 ±313.03)ms,( 1433.20 ±342.23) ms,respectively) and HC group( (797.27 ±216.97)ms,( 794.11 ± 209.41 ) ms,(799.40 ± 215.82 ) ms respectively) on the reaction time of neutral,negative and alcohol-related words were significant ( t =8.822,P ＜ 0.001 ; t =8.922,P ＜ 0.001 ; t =9.234,P ＜ 0.001 ).The error number of of the neutral and negative- related words of the patients ( ( 3.70 ± 2.56) time,( 4.23 ± 2.53 ) time)was worse than that of HC group( ( 2.11 ± 1.87 ) time,( 1.92 ± 1.82 ) time) ( t =2.939,P =0.005 ; t =4.355,P ＜0.01 ).Error number of the alcohol- related words between two groups were not significant;Its alcohol-related words attentional bias negative correlation to the age of initial alcohol use(P＜ 0.05 ),and positive correlation to continue drinking and score of self-rating depression scale (P＜0.05).Age of addiction and the score of self-rating anxiety scale enter the regression equation of alcohol-related words.ConclusionThese results demonstrate that alcoholics have attentional bias in alcohol-related words and reward-related brain regions may be associated with craving among male patients with attentional bias.
