Evaluation of the Tosoh HLC-723 G8 HbA1c Autoanalyzer.
- Author:
Aerin KWON
1
;
Ji Young PARK
;
Jae Seok KIM
Author Information
1. Department of Laboratory Medicine, Hallym University College of Medicine, Chuncheon, Korea. parkjy@hallym.or.kr
- Publication Type:Original Article
- Keywords:
HbA1c;
Ion-exchange HPLC;
Tosoh HLC-723 G8
- MeSH:
Chromatography, High Pressure Liquid;
Humans;
Outpatients;
Tokyo
- From:Journal of Laboratory Medicine and Quality Assurance
2008;30(2):273-277
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: We evaluated overall performance and analysis time of newly developed HLC-723 G8 (Tosoh corp., Tokyo, Japan) HbA1c autoanalyzerwhich utilizes cation-exchange HPLC method. METHODS: Linearity, precision, correlation with Variant II Turbo (Bio-Rad Laboratories, Hercules, CA, USA), analysis time, labile HbA1c (L-A1c) separation ability and stability of refrigerated sample at 4degrees C were evaluated. RESULTS: HLC-723 G8 showed good linearity between HbA1c 4.9-12.0% range (R2=0.9995). Within-run and total imprecision (CVs) were less than 1.0%. Correlation with Variant II Turbo and L-A1c separation ability were excellent. Analysis time per sample took 1.0 min. Stability of refrigerated sample at 4degrees C for at least 21 days was good. CONCLUSIONS: HLC-723 G8 showed good analytical performance and its rapid analysis time enables us to support outpatient diagnosis of diabetic patients efficiently.
