Influence of drip velocity of nitrate on blood pressure of patients with coronary heart disease
10.3760/cma.j.issn.1672-7088.2012.20.059
- VernacularTitle:硝酸酯类静脉滴注速度对冠心病患者血压的影响
- Author:
Ruilan YANG
;
Zhenhuan REN
;
Huimin REN
;
Miaomiao LI
;
Qiaoling MAO
;
Xiying YAN
;
Xiaoyun YUE
- Publication Type:Journal Article
- Keywords:
Nitroglycerin;
Isesorbide mononitrate;
Coronary heart disease;
Systolic pressure;
Diastolic pressure
- From:
Chinese Journal of Practical Nursing
2012;28(20):19-21
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the relationship of drip velocity of nitrate on blood pressure while treating coronary disease,in order to provide appropriate drip velocity for clinical treatment.Methods 155 patients with coronary disease using nitrate to lower blood pressure were selected.They were divided into the nitro glycerin group(85 cases) and the isosorbide mononitrate group( 70 cases) according to difference of medication.The velocity of drugs was adjusted on basis of blood pressure changes.The blood pressure changes at different drip velocities were observed and compared.Results The systolic pressure and the diastolic pressure between two groups showed no difference at 20 drops/min,but the results were the opposite at 30 drops/min.The systolic pressure and the diastolic pressure in the nitro glycerin group showed evident changes at different drip velocities,but in the isosorbide mononitrate group,these changes were not so significant.9 patients in the nitro glycerin group had headache during treatment,no headache occurred in the isosorbide mononitrate group.Conclusions Intravenous use of nitrate at a velocity of 20 drops/min is relative secure.The risk of hypotension will increase if the medication speed increases.lsosorbide mononitrate has little influence on blood pressure.
