Clinical analysis of hemodialysis combined with hemoperfusion in the treatment of uremic pruritus
10.3760/cma.j.issn.1673-4904.2012.18.006
- VernacularTitle:血液透析联合血液灌流治疗尿毒症皮肤瘙痒的临床分析
- Author:
Peng ZHANG
;
Shuqian DONG
- Publication Type:Journal Article
- Keywords:
Uremia;
Pruritus;
Renal dialysis;
Perfusion
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(18):15-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of hemodialysis (HD) combined with hemoperfusion (HP) in the treatment of uremic pruritus.Methods The clinical data of 96 patients with uremic pruritus were analyzed retrospectively.All cases were treated with HD combined with HP.Results Pruritus score before and after treatment was (9.3 + 0.7) scores and (4.9 + 0.6) scores,respectively.And there was statistical significance (P ＜0.05).The erum creatinine,urea nitrogen,parathormone and β2 microglobulin before treatment were (712 ±148) μmol/L,(17.7 ±3.8) mmol/L,(47.1 ±12.4) ng/L,( 27.4 + 5.6 ) μ mol/L,respectively,and after treatment they were ( 324 ± 84 ) μ mol/L,( 7.4 ± 2.3 ) mmol/L,(15.6±5.1) ng/L,(11.1 ±2.2) μmol/L,there were statistical significance (P＜0.05).Conclusions HD combined with HP can effectively lighten the pruritus.It is worthy of clinical application.
