The differential diagnosis value of sICAM-1, VEGF and CRP in benign and malignant pleural effusion

VernacularTitle:可溶性细胞黏附分子1、血管生长因子、C反应蛋白联合检测在胸腔积液鉴别诊断中的价值
Author: Hongze ZHENG ; Cuie QU
Publication Type:Journal Article
Keywords: Cell adhesion molecules; Angiogenesis; C-reactive protein; Pleural effusion
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(13):1968-1969
CountryChina
Language:Chinese
Abstract: Objective To discuss the differential diagnosis value of sICAM-1,VEGF and CRP in benign and malignant pleural effusion.Methods The levels of sICAM-1,VEGF and CBP were detected in 46 cases of malignant pleural effusion and 43 cases of benign pleund effusion.Results The levels and positive rates of sICAM-1,VEGF in malignant pleural effusion group was significantly higher than those in benign pleural effusion group ( t =7.125、6.271,x2 =33.929,all P ＜ 0.05 ),while CRP was significantly lower than that in benign effusion group ( t =5.963,x2 =31.430,all P ＜0.05).Conclusion The levels of sICAM-1,VEGF and CBP were significantly different between benign and malignant pleural effusion,which could be selected as the indexes for discriminating benign and malignant pleural effusion.