Palpitation- hepatosplenomegaly- ascites: a case report and literature review

VernacularTitle:第3例:阵发性心慌-肝脾肿大-腹水
Author: Jianqiu ZHAO ; Xiangdong LU ; Zhiguang ZHANG ; Yong JIANG
Publication Type:Journal Article
From: Chinese Journal of Geriatrics 2012;31(8):726-728
CountryChina
Language:Chinese
Abstract: This report presented a case of 62-year-old woman who was admitted to our hospital for cirrosis, but she had a variety of clinical manifestations,such as abdominal distension,diarrhea,ascites, hepatosplenomegaly,anemia, palpitation, flushing, low blood pressure, arrhythmia and so on. Upper gastrointestinal endoscopy showed thicken mucosa at gastric fundus. Colonoscopy revealed nodular, pseudopolypoid. Ascitic fluid test suggested a transudate. Endoscopic abnormal mucosa biopsy showed chronic inflammation. Many mast cells were seen in bone marrow and liver biopsies,and liver tissue immunophenotype was CD117, and CD68. Thus the patient's diagnosis was systemic mastocytosis. It is rare that a patient only has the gastrointestinal tract symptoms complicated with ascites without skin lesion. The goal for treatment was to reduce hypersecretion of mast cells.