Efficacy of transurenthral resection of muscle-invasive bladder cancer in the elderly
10.3760/cma.j.issn.0254-9026.2012.07.012
- VernacularTitle:老年肌层浸润膀胱癌患者行经尿道电切术的疗效评价
- Author:
Hong GAO
;
Yan LIU
;
Zexing WANG
;
Aiwu MA
;
Dawei CUI
- Publication Type:Journal Article
- Keywords:
Urologic surgical procedures;
Urinary bladder neoplasms
- From:
Chinese Journal of Geriatrics
2012;31(7):586-588
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effects of transurenthral resection of muscleinvasive bladder tumor (TURBT) in senile. Methods This study was clinical prospective random research.46 senile cases with muscle-invasive bladder cancer treated by TURBT was divided into 2 groups:control group and observed group.The observed group was treated with TURBT combined with intravesical instillation of pirarubi 30 mg immediately after TURBT,the bladder wall around tumor was resected thoroughly.The control group underwent radical cystectomy and pelvic lymph node dissection. Results The clinical improvement rate was higher in observed group than control group (85.7％ s.63.6％,X2 =5.3008,P=0.021).There was not difference in 3 years recurrence rate between observed group(25.0％) and control group(13.6％) (x2 =S.3008,P＞0.05).The 1 year survival rate were 95.8％,90.9％ and 3 years survival rate were 79.2％,72.7％ in observed group and control group,respectively,and there were no differences between the two groups(X2 =0.262,P=0.609). Conclusions TURBT combined with intravesical instillation of pirarubi can enhance clinical effect and reduce recurrence rate in the treatment of the elderly with muscle-invasive bladder cancer.
