The correlation of the abnormal level of maternal serum-free β-human chorionic gonadotropin during second-trimester pregnancy and adverse pregnancy outcome
10.3760/cma.j.issn.1673-4904.2012.18.007
- VernacularTitle:妊娠中期母体血清游离β-人绒毛膜促性腺激素水平异常与不良妊娠结局的相关性
- Author:
Fei CHEN
- Publication Type:Journal Article
- Keywords:
Pregnancy trimester,second;
Chorionic gonadotropin,beta subunit,human;
Pregnancy outcome
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(18):17-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the copulation of the abnormal level of maternal serum-free β-human chorionic gonadotropin ( β-hCG ) during second-trimester pregnancy and adverse pregnancy outcome.Methods Two hundred and nine pregnant women in second-trimester pregnancy were detected serum β-hCG and followed up ti11 delivery.The correlation of the abnormal level of serum β-hCG and adverse pregnancy outcome were observed.Results In 209 pregnant women,the level of serum β -hCG of 105 cases were over standard [(84.9 ± 11.6) kU/L](over standard group),while the level of the rest 104 cases were (18.6 ± 1.3) kU/L within normal range (normal group).The incidence rate of gestational hypertension,premature deliwery,premature rupture of membranes and suffocation of new born infants in over standard group were all higher than those in normal group [14.3％(15/105 ) vs.0,18.1％(19/105) vs.2.9％ (3/104),11.4％(12/105) vs.0,29.5％(31/105) vs.0,P＜0.05].Conclusions The abnormality of serum β -hCG of women in second-trimester pregnancy can reflect the placenta dysfunction and it is a signal of adverse pregnancy outcome.Therefore,detecting the level of serum β -hCG is useful for preventing adverse pregnancy outcome.
