Tumor multidrug resistance and apoptosis evasion
10.3760/cma.j.issn.1673-422X.2012.07.001
- VernacularTitle:肿瘤多药耐药与细胞凋亡逃逸
- Author:
Fei SUN
;
Chen QING
- Publication Type:Journal Article
- Keywords:
Drug resistance,neoplasm;
Apoptosis;
Tumor escape
- From:
Journal of International Oncology
2012;39(7):483-485
- CountryChina
- Language:Chinese
-
Abstract:
Most anticancer drugs inhibit tumor cell growth by inducing apoptosis.Apoptosis-evasion,also enhancement of anti-apoptosis ability(e.g.anti-apoptosis related genes over-expression or pro-apoptotic related genes loss,etc.)may lead to tumor cell multidrug resistance.Many researches show that apoptosis-evasion is one of the important factors resulting in tumor multidrug resistance.
