Effect of adiponectin in malignant tumor neovascularization
10.3760/cma.j.issn.1673-422X.2012.07.005
- VernacularTitle:脂联素对肿瘤新生血管的作用
- Author:
Ruobing MA
;
Yuelong PAN
;
Jian WANG
- Publication Type:Journal Article
- Keywords:
Adiponectin;
Neoplasms;
Neovascularization pathologic;
Angiogenesis inhibitors
- From:
Journal of International Oncology
2012;39(7):497-500
- CountryChina
- Language:Chinese
-
Abstract:
Adiponectin is recently described as an adipocyte secreting cytokine,which is abundant in human plasma,Adiponectin plays important roles not only in glucose and lipid metabolism but also in the development and progression of several obesity-related malignancies.Vascular formation is a key step in the cancer growth and metastasis.Current reserches find that the effect of adiponectin in cancer vascular growth still has great differenees.This review discusses the effect of adiponectin in malignant tumor neovascularization,and reveals that adiponectin can be a new vasoinhibitor.
