Role of β-adrenergic receptor in the occurrence and development of tumor
10.3760/cma.j.issn.1673-4203.2012.07.014
- VernacularTitle:β-肾上腺素能受体在肿瘤发生发展中的作用
- Author:
Zhen HE
;
Shutian ZHANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Receptors,adrenergic,beta;
Adrenergic beta-antagonists
- From:
International Journal of Surgery
2012;39(7):475-478
- CountryChina
- Language:Chinese
-
Abstract:
The β-adrenergic receptor has close relationship with the occurrence and development of tumor.The β-adrenergic receptors were expressed in a variety of tumors.Its activation can stimulate tumor growth by promoting cell proliferation,inhibite apoptosis,promote angiogenesis,and enhance tumor invasion and metastasis.The β-adrenergic receptor blockers can suppress the tumor growth,which may become one of the effective methods of cancer prevention and treatment.