Regulatory relationships between microRNAs and DNA methylafion in gastric cancer
10.3760/cma.j.issn.1673-422X.2012.07.015
- VernacularTitle:胃癌中微小RNA与DNA甲基化调控的关系
- Author:
Yongjuan GU
;
Qiu ZHAO
;
Renhua GUO
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
MicroRNAs;
DNA methylation
- From:
Journal of International Oncology
2012;39(7):529-532
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs(miRNAs)are a class of small(22 nucleotides)non-coding RNAs which play important roles in diverse biological and pathological processes.The dysregulation of miRNA expression is closely related to the development and progression of malignant tumors in humans.DNA methylation is a kind of epigenetic modification in human genome.Both hypermethylation and hypomethylation of DNA are closely related to different kinds of tumors,including gastric cancer.
