Small interfering RNA in gastrointestinal cancer
10.3760/cma.j.issn.1673-422X.2012.07.017
- VernacularTitle:小干扰RNA在胃肠道肿瘤中的研究进展
- Author:
Feng JU
;
Junbo ZUO
;
Jiazeng XIA
- Publication Type:Journal Article
- Keywords:
RNA;
small interfering;
RNA interference;
Gastrointestinal neoplasms
- From:
Journal of International Oncology
2012;39(7):538-540
- CountryChina
- Language:Chinese
-
Abstract:
SiRNA comes from double-stranded RNA,which is processed into a small molecular fragment by Dicer.21-25nt siRNA,as the key effector molecules to the RNAi process,can inhibit gene expression with high specificity and high efficiency in mammalian cells.Currently,RNAi has been widely applied in a variety of cancer.RNAi has many active research explorations of the tumor development,metastasis and treatment in gastrointestinal cancer.
