Association of peripheral white blood cell with type 2 diabetic nephropathy
10.3760/cma.j.issn.1671-7368.2012.07.022
- VernacularTitle:外周血白细胞与糖尿病肾病进展关系的研究
- Author:
Xueyang ZHANG
;
Xiaozhen LIU
;
Ran BAI
;
Yongbo WANG
;
Jianling DU
;
Changchen LI
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathies;
Leukocytes
- From:
Chinese Journal of General Practitioners
2012;(7):528-529
- CountryChina
- Language:Chinese
-
Abstract:
A total of 473 patients of diabetic nephropathy (DN) with normal serum creatinine were recruited.Blood routine,blood lipids and urine albumin/creatinine ratio (UACR) were measured.They were divided into microalbuminuria group (DN1,n =246 ) and macroalbuminuria group (DN2,n =227 ).The white blood cell (WBC) count,monocyte count and CRP significantly increased with the progression of DN in the DN2 group versus those in the DNI group [ (6.8 ± 1.7 ) × 109/L vs.(6.3 ± 1.5 ) × 109/L,(0.49±0.23) ×109/Lvs.(0.32 ±0.21) ×109/L,(4.1 ±1.1)mg/Lvs.(1.7±0.3) mg/L,all P＜ 0.05].According to multiple linear regression analysis,WBC,monocyte,low density lipoproteincholesterol and lymphocyte were found to be independent influencing factors for the elevation of UACR.
