Negative effects of protein tyrosine phosphatase SHP-1 in cell signaling
10.3760/cma.j.issn.1673-422X.2012.07.002
- VernacularTitle:蛋白酪氨酸磷酸酶SHP-1在细胞信号系统中的负调控作用
- Author:
Gang PENG
;
Rubo CAO
;
Gang WU
- Publication Type:Journal Article
- Keywords:
Protein-tyrosine kinases;
Signal transduction;
Immune system;
Hematopoietic system
- From:
Journal of International Oncology
2012;39(7):485-488
- CountryChina
- Language:Chinese
-
Abstract:
SHP-1 is the protein tyrosine phosphatase which is mainly expressed in the cytoplasm of hematopoietic-derived cells,and it is the key factor to change the levels of intracellular phosphorylation.SHP-1 can generate different intracellular signals in different cells,and it can play various functions.
