Cancer cachexia diagnosis and therapy
10.3760/cma.j.issn.1673-422X.2012.07.009
- VernacularTitle:癌性恶病质的诊断和治疗
- Author:
Zifeng LIU
;
Guixin LI
- Publication Type:Journal Article
- Keywords:
Cachexia;
Diagnosis;
Neoplasm staging;
Proteasome
- From:
Journal of International Oncology
2012;39(7):510-513
- CountryChina
- Language:Chinese
-
Abstract:
Cancer cachexia(CC)caused by cancer is a syndrome with complicated symptoms.Traditional therapies usually give interventions for more nutrition intake at CC late stage and take weight as the outcome marker.Lots of clinical trials demonstrate that the effect is not satisfactory.Recent studies show that the level of NF-KB decreased,termination of the breakdown of myofibrillar proteins,the serum proteins and lean body mass increased and function improvement after targeting proteasome at early stage of CC combined with traditional therapy.
