Distribution of metastatic lymph nodes in 150 patients who underwent radical resection for pancreatic head cancer
10.3760/cma.j.issn.1007-8118.2012.07.002
- VernacularTitle:根治性切除胰头癌150例患者淋巴结转移的分布和特点
- Author:
Yongjian JIANG
;
Jiuliang YAN
;
Chen JIN
;
Zhongwen ZHOU
;
Feng YANG
;
Yang DI
;
Ji LI
;
Lie YAO
;
Sijie HAO
;
Feng TANG
;
Deliang FU
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms;
Pancreaticoduodenectomy;
Lymphatic metastasis;
Surgical microscope
- From:
Chinese Journal of Hepatobiliary Surgery
2012;18(7):494-498
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the characteristics and the impact of lymph node metastasis on radical resection for pancreatic head cancer to provide a theoretical basis for lymphadenectomy in radical resection.To study the reliability of using a surgical microscope to detect lymph nodes in radically resected specimens of pancreatic head cancer.MethodsLymph nodes in the specimens after radical pancreaticoduodeneetomy (pancreaticoduodenectomy + D2 regional lymphadenectomy) were identified using a surgical microscope and they were grouped using the JPS standard.The position and the frequency of the lymph nodes retrieved,and their association with other clinicopathologic factors were analysed.The results were compared with the data published in 2004 on 46 patients to evaluate the reliability of using a surgical microscope.ResultsLymph node metastasis was detected histopathologically in 101 patients (67.3％).The median number of lymph nodes retrieved in the specimens as detected using the surgical microscope was 38.2.The most commonly involved lymph node groups were No.13 (64.5％),No.14 (51.7％),No.17 (38.6％),No.12 (25.8％),No.16 (20.8％).Lymph node metastasis was significantly associated with tumour T stage,tumour invasion and differentiation,preoperative serum level of CA19-9 and CA72-4,but not with patient age,sex,or tumour location.There were no significant differences between the results and the data of the previous study in 2004.ConclusionsExtended lymphadenectomy is necessary because extensive lymph node metastasis was common.Surgical microscopy is an effective and reliable method to detect lymph nodes in resected specimens of pancreatic head cancer for accurate pathologic staging.
