Using bone marrow mesenchymal stem cells to treat liver diseases
10.3760/cma.j.issn.1007-8118.2012.07.023
- VernacularTitle:骨髓间充质干细胞在肝脏疾病治疗中的应用
- Author:
Jian CHU
;
Hualian HANG
;
Yabin YU
;
Shihai ZHANG
;
Jianmin BIAN
- Publication Type:Journal Article
- Keywords:
Bone marrow mesenchymal stem cells;
Liver cancer;
Liver regeneration;
Tumor metastasis
- From:
Chinese Journal of Hepatobiliary Surgery
2012;18(7):564-566
- CountryChina
- Language:Chinese
-
Abstract:
Primary hepatocellular carcinoma progresses from liver fibrosis and cirrhosis to eventually result in liver failure and distant metastasis.Surgical resection is the preferred method of treatment for liver cancer while interventional treatment and liver transplantation are the choices to treat end-stage liver cancer.Unfortunately,partial hepatectomy and interventional treatment are not ideal due to the resulting consequence of hepatocyte dysfunction.Extensive clinical application of liver transplants is limited by the lack of available donors and high costs.Over the past decade,researches on bone marrow mesenchymal stem cells (BMSCs)have made remarkable achievements in the medical field.In this review,we summarize the recent progress of BMSCs in the treatment of liver diseases.
