A Case of Sarcoidosis with Diabetes Inspidus.
- Author:
Byung Hwan CHUN
1
;
Seong Jun SEO
;
Chang Kwun HONG
;
Byung In RO
;
Sung Ho HUE
Author Information
1. Department of Deramtology, Chung-Ang University, College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Diabetes inspidus;
Sarcoidosis
- MeSH:
Biopsy;
Central Nervous System;
Dermatology;
Dermis;
Forehead;
Granuloma;
Humans;
Incidence;
Internal Medicine;
Lung;
Lymph Nodes;
Male;
Middle Aged;
Polydipsia;
Polyuria;
Sarcoidosis*;
Skin;
Subcutaneous Tissue;
Water Deprivation;
Weight Loss
- From:Korean Journal of Dermatology
1997;35(5):1013-1017
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sarcoidosis, a multisystemic disease of unknown cause characterized by the formation of noncaseat,ing granulomas, may involve any organ of the body. The most common sites of predilection are the lungs, lymph nodes, skin and eyes. Cutaneous sarcoidosis is seen in approximately 20-35% of patients with systcmic disease. Involvement of the central nervous system with sarcoidosis is relatively uncommon with an estimated incidence of only 3.5-5.0%. A 57-year-old male had been admitted to Department of Internal Medicine due to weight loss, polydipsia, polyuria, visual disturbance and bilateral hilar enlargement. He was diagnosed as sarcoidosis with diabetes inspidus by mediastinoscopic biopsy and a water deprivation test. On his first visit to dermatology he had several well-demarcated smooth-surfaced erythematous plaques on his forehead which had been there for 7 months. Histopathologically, many noncaseating epithelioid tubercles which are characteristic findings of sarcoidosis, were found in the dermis and subcutaneous tissue. We treated him with predniscilone 40 mg daily for 3 months and skin lesions markedly improved.
