The role of preoperative CA19-9 level in predicting resectability of pancreatic cancer
10.3760/cma.j.issn.1007-8118.2012.06.012
- VernacularTitle:血清癌抗原19-9水平对胰腺癌可切除性判断的临床意义
- Author:
Guopei LUO
;
Jiang LONG
;
Chen LIU
;
Jin XU
;
Xianjun YU
;
Quanxing NI
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms;
Tumor markers;
biological;
CA-19-9 antigen;
Pancreatectomy
- From:
Chinese Journal of Hepatobiliary Surgery
2012;18(6):436-438
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the role of preoperative CA19-9 level in predicting resectability of pancreatic cancer.Methods Preoperative CA19-9 levels were determined by radioimmunoassay.The receiver operating characteristic curve was used to determine the cut-off point.The clinical value of the level of CA19-9 as a predictive marker of resectability was evaluated by the area under curve.Results The preoperative CA19-9 levels in the resectahle group was (313.6±515.5) kU/L,which was significantly lower than (852.1± 865.1)kU/L in the unresectable group (P＜0.001).The cut-off point of CA19-9 for predicting pancreatic cancer resectability was 312.1 kU/L,which had a sensitivity of 56.6％ and a specificity of 73.3％.The area under curve was 0.67.Conclusions The preoperative CA19-9 level may be used to predict resectability of pancreatic cancer.
