Chondroitin sulfate proteogly can and the plasticity of central nervous system
10.3760/cma.j.issn.1673-4165.2012.05.012
- VernacularTitle:硫酸软骨素蛋白多糖与中枢神经系统可塑性
- Author:
Xinran CHEN
;
Jian YU
- Publication Type:Journal Article
- Keywords:
Chondroitin Sulfate Proteoglycans;
Neuronal Plasticity;
Central Nervous System;
Nerve Regeneration;
Chondroitin ABC Lyase
- From:
International Journal of Cerebrovascular Diseases
2012;20(5):378-383
- CountryChina
- Language:Chinese
-
Abstract:
Chondroitin sulfate proteoglycan (CSPG) is a group of extracellular matrix molecules expressed widely in the developing and mature central nervous system (CNS).They play an important role during embryonic CNS development and adult CNS plasticity.As a major extracellular inhibitory compound,CSPG can affect the axon regeneration and neurological recovery after CNS injury.