The genetic polymorphisms of mannose binding lectin and Kawasaki disease
10.3760/cma.j.issn.1673-4408.2012.03.001
- VernacularTitle:甘露糖结合凝集素基因多态性与川崎病
- Author:
Shulai ZHOU
- Publication Type:Journal Article
- Keywords:
Mannose binding lectin;
Genetic polymorphisms;
Kawasaki disease
- From:
International Journal of Pediatrics
2012;39(3):217-219
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease(KD) is a common autoimmune disease in children.KD is characterized as a systemic artcriolar inflammatory,but its pathogenesis is still not clear.In recent years,many studies have shown KD is associated with the polymorphisms of multiple genetic fragments.The relationship between mannose binding lectin(MBL) gene and KD has attracted much attention.This review introduces the construction and function of MBL briefly,and focuses on the relationship between the genetic polymorphisms of MBL and susceptibility,cardiovascular damage of KD.
