Progress of programmed cell death 5 gene and tumors
10.3760/cma.i.issn.1673-4408.2012.04.007
- VernacularTitle:PDCD5基因与肿瘤关系的研究进展
- Author:
Yiqiao CHEN
- Publication Type:Journal Article
- Keywords:
PDCD5;
Tumor;
Apoptosis
- From:
International Journal of Pediatrics
2012;39(4):348-351
- CountryChina
- Language:Chinese
-
Abstract:
Programmed cell death 5 ( PDCD5 ),formerly designated as TFAR19 ( TF-1 cell apoptosis-related gene 19),is an apoptosis-regulated gene cloned by Peking University Center for Human Disease Genomics.PDCD5 is expressed in many human tissues,with a high degree of homology,plays a regulatory role during cell apoptosis.Disorders of PDCD5 expression is correlated with tumorigenesis.This article reviews the structure,expression and functions of PDCD5,makes a summary of its relationship with kinds of tumors.Further studies about clinical application of PDCD5 are needed.
