Applications of intravenous balanced propofol sedation with fentanyl in elderly patients during combined gastroscopy and colonoscopy procedures
10.3760/cma.j.issn.0254-9026.2012.06.013
- VernacularTitle:异丙酚静脉复合麻醉在老年人胃肠镜联合检查中的应用
- Author:
Qingfeng LUO
;
Hongjun DUAN
;
Le XU
- Publication Type:Journal Article
- Keywords:
Endoscopy,gastrointestinal;
Anesthesia,intravenous;
Propofol
- From:
Chinese Journal of Geriatrics
2012;31(6):488-490
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safety of intrvenous balanced propofol sedation with fentanyl in elderly patients during combined gastroscopy and colonoscopy procedures.Methods Totally 877 elderly patients aged (76.4 ± 8.5) years received intravenous propofol and fentanyl sedation during gastroscopy or/and colonoscopy procedures were assigned to groups:294 cases with only gastroscopy,257 cases with only colonoscopy and 326 cases with combined gastroscopy and colonoscopy.50 g Fentanyl and 0.5-1.0 mg/kg propofol were intravenously administered in the patients.The peripheral oxygen saturation,arterial pressure and heart rate were monitored and recorded during procedures.Results There were no procedure-related perforations and sedationassociated severe complications and mortalities,and no one need stop endoscopy procedures in all the patients.The average dosage of propofol in combined,gastroscopy and colonoscopy groups were (100.4±38.5) mg,(130.4±50.5)mg and (170.3± 60.3)mg,respectively.There were no significant differences in heart rate,arterial pressure and rate of cardiovascular events among groups (P＞0.05).The rate of respiration events in the above groups were 9 cases(3.1％),6 cases(2.3％)and 13 cases(4.0％),respectively (P＞0.05).Decrease of peripheral oxygen saturation was mainly induced by the aspiration of oral secretions and snoring.Conclusions Intravenous balanced propofol sedation provides safe and effective sedation in the elderly undergoing combined gastroscopy and colonoscopy.
