The role of mizoribine in kidney diseases
10.3760/cma.j.issn.1673-4408.2012.03.011
- VernacularTitle:咪唑立宾在肾脏疾病中的应用
- Author:
Qian HUANG
- Publication Type:Journal Article
- Keywords:
Mizoribine;
Kidney transplantation;
Lupus nephritis;
IgA nephropathy;
Nephrotic syndrome
- From:
International Journal of Pediatrics
2012;39(3):252-254
- CountryChina
- Language:Chinese
-
Abstract:
Mizoribine,an immunosuppressive agent,plays a role in cell synthesis process,selectively inhibits lymphocyte proliferation,and suppresses immune function.It has obtained certain curative effect in resistance the rejection after kidney transplantation,slowing down lupus nephritis pathological progress,reducing the proteinuria and the risk of glomerular sclerosis on IgA nephropathy,decreasing the recurrence frequency and proteinuria on steroid-dependent nephrotic syndrome and reducing proteinuria level on Henoch-Schoenlein purpura nephritis.It's safer,fewer side effects,but for lacking evidences,large sample still be needed.
