How to extend the thrombolytic time window for acute ischemic stroke?
10.3760/cma.j.issn.1673-4165.2012.05.009
- VernacularTitle:如何延长急性缺血性卒中溶栓治疗时间窗?
- Author:
Xiaoning WU
;
Lianqiu MIN
;
Yumin LUO
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain Ischemia;
Thrombolytic Therapy;
Fibrinolytic Agents;
Neuroprotective Agents;
Time Factors
- From:
International Journal of Cerebrovascular Diseases
2012;20(5):362-367
- CountryChina
- Language:Chinese
-
Abstract:
Currently,thrombolytic therapy is the most effective treatment for acute ischemic stroke.Intravenous recombinant tissue plasminogen activator administered within 3 hours of symptom onset is the only medication approved by U.S.Food and Drug Administration for the treatment of acute ischemic stroke.However,because the time window for intravenous thrombolytic therapy is very short,only a very few patients can reach the hospital for intravenous thrombolytic therapy within 3 hours of onset.Therefore,how to extend the time window of thrombolytic therapy for more patients to have accessed to it and benefit from it have been the concern of researchers.This article reviews about the recent advances in research on extending the time window of thrombolytic therapy.