Kawasaki disease and allergic diseases
10.3760/cma.j.issn.1673-4408.2012.03.006
- VernacularTitle:川崎病与过敏性疾病的关系
- Author:
Han ZHANG
- Publication Type:Journal Article
- Keywords:
Kawasaki disease;
Allergic diseases
- From:
International Journal of Pediatrics
2012;39(3):234-236
- CountryChina
- Language:Chinese
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Abstract:
Kawasaki disease (KD) is one of the most common causes of acquired heart disase in children,the development of which is closely related to the allergic diseases.Recent studies have manifested that the incidence of allergic diseases in children with KD is far higher than that in those children without KD.Meanwhile,the morbidity of KD in allergic children is significantly higher than that in those who do not have family medical history of allergic diseases.By far,the mechanisms causing interaction between KD and allergic diseases still remain unclear.Possible mechanisms include IgE-meditated immune response,release of large quantity of cytokines and inflammatory meditators as well as atopic family history.