Clinical study of prognosls evaluation of brainstem auditory evoked potential combined with mesencephalic morphology on coma patients with severe craniocerebral injury
10.3760/cma.j.issn.1673-4904.2012.17.001
- VernacularTitle:脑干听觉诱发电位联合中脑形态对重型颅脑损伤昏迷患者预后评估的临床研究
- Author:
Lei WANG
;
Fu HUANG
;
Qinghua ZHANG
;
Zhenlin ZHAO
;
Dong HU
;
Hua XIAO
- Publication Type:Journal Article
- Keywords:
Evoked potentials,auditory,brainstem;
Tomography,X-ray computed;
Craniocerebral trauma;
Prognosis
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(17):1-4
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between brainstem auditory evoked potential (BAEP) combined with mesencephalic morphology and the prognosis of coma patients with severe craniocerebral injury.Methods Forty-seven coma patients with severe craniocerebral injury were examined with BAEP and moaitored dynamically in early period of coma,and all these patients got head CT scans and the ratio of anteroposterior diameter and transverse diameter of mesencephalon were measured at the same time.Results There was a significantly negative relationship between the first BAEP classification and GOS score at the end of the follow-up (r =-0.755,P =0.000 ).Among all of the patients,there were 27 patients with the ratio of anteroposterior diameter and tansverse diameter of mesencephalon from 0.9 to 1.1,19 patients (70.4％,19/27) with good prognosis;20 patients with the ratio ＞1.1 or ＜ 0.9,6 patients (30.0％,6/20 ) with good prognosis.The rate of good prognosis between the two had significant difference ( x2 =7.521,P =0.006).The sensitivity and specificity were 73.7％(14/19),82.6％ (19/23) at the first BAEP combined with mesencephalic morphology,88.2％ (15/17),100.0％ (21/21) at the second BAEP combined with mesencephalic morphology.Conclusion BAEP combined with mesencephalic morphology can evaluate effectively the prognosis of coma patients with severe craniocerebral injury.
