Study on the effect of different treatments for breast cancer patients
10.3760/cma.j.issn.1008-6706.2012.09.032
- VernacularTitle:不同化疗方案治疗乳腺癌临床效果比较
- Author:
Yong JIANG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Gemcitabine;
Vinorelbine;
Cisplatin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(9):1343-1344
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of different treatments for breast cancer patients.Methods The clinical date of 24 patients with breast cancer were retrospectively analyzed.According to treatment method,24 patients were divided into 2 groups,control group of 12 patients received,and vinorelbine plus cisplatin.Experimental group of 12 patients received gemcitabine plus cisplatin.Both groups were treated for 6 weeks,follow-up in JanuaryFebruary,after treatment the short-term efficacy and toxicity were observed.Results During follow-up compared betwween two groups,after 6 weeks of treatment in patients with overall response rate ( complete response + partial response) are better than 1 week after treatment,the difference was statistically significant( P ＜0.05 ) ;between the two groups compared after treatment,experimental group patients overall efficiency as better than the control group,but had no statistically significant difference( P ＞ 0.05 ).In the control group,Ⅲ + Ⅳ leukopenia,nausea,vomiting and phlebitis rate were relatively high than experimental group,experimental group Ⅲ +Ⅳ thrombocytopenia was higher than control group,the differences were statistically significant( P ＜0.05 ).Conclusion Early application of gemcitabine plus cisplatin in patients with breast cancer could significantly improve,the survival and prognosis,improve patients quality of life,and safe,it's worthy of promoting in clinic.
