Effect of serum autoantibodies in the early diagnosis of cancer
10.3760/cma.j.issn.1673-422X.2012.06.008
- VernacularTitle:血清自身抗体在肿瘤早期诊断中的作用
- Author:
Yuhui PENG
;
Yiwei XU
- Publication Type:Journal Article
- Keywords:
Autoantihodies;
Neoplasms;
Early diagnosis
- From:
Journal of International Oncology
2012;39(6):425-428
- CountryChina
- Language:Chinese
-
Abstract:
At present,the commonly used tumor markers,with low sensitivity and low specificity,can 't achieve the purpose of early diagnosis.However,autoantibodies against tumox-associated antigens have been detected in the asymptomatic stage of cancer and thus can serve as biomarkers for early cancer diagnosis.Moreover,due to autoantibodies are found in sera,they can he screened easily using a noninvasive approach.The discovery of panels of autoantibodies with high sensitivity and specificity will help to improve the diagnostic and prognostic for the patients with cancer.
