Toxicities of targeted therapy in renal cancer and their treatment strategies
10.3760/cma.j.issn.1673-422X.2012.06.014
- VernacularTitle:肾癌靶向治疗的常见不良反应及其治疗策略
- Author:
Xiaorong WU
;
Dongming LIU
- Publication Type:Journal Article
- Keywords:
Kidney neoplasms;
Drug therapy;
Adverse effects
- From:
Journal of International Oncology
2012;39(6):445-448
- CountryChina
- Language:Chinese
-
Abstract:
With the indepth studies of molecular mechanisms of renal cell carcinoma ( RCC),people have made great progress in the targeted therapy drugs which targeted at vascular endothelial growth factor (VEGF) and their receptors,which dramatically improve the treatment outcome for patients with advanced or metastatic RCC.However,recent clinical trails show that the targeted therapy drugs may cause adverse events,such as hypertension,bone marrow toxicity,pneumonitis and so on.It is important to manage the adverse events promptly not only to improve the therapeutic efficacy but also to improve the quality of life for patients with RCC.
