The relationship between excessive daytime sleepiness and the quality of life in patients with moderate to severe obstructive sleep apnea and hypoventilation syndrome
10.3760/cma.j.issn.1008-6706.2012.09.001
- VernacularTitle:中重度睡眠呼吸暂停低通气综合征患者白天嗜睡与生活质量的关系
- Author:
Xuefeng LI
;
Jianwei LIU
;
Song LIU
;
Huifen ZHAI
;
Ying CHEN
;
Zhengyi HE
- Publication Type:Journal Article
- Keywords:
Sleep apnea,Obstructive;
Quality of life
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(9):1281-1282
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association of excessive daytime sleepiness(EDS) and the quality of life in patients with moderate to severe obstructive sleep apnea and hypoventilation syndrome (OSAHS).Methods 123 patients with moderate to severe OSAHS were diagnosed by polysomnography(PSG),and 52 cases ruled out by PSG were controls.Patients and controls were completed the Calgary sleep apnea quality of life index (SAQLI) and the Epworth sleepiness score(ESS).Results There were statistical significance of body mass index (BMI),respiratory disturbance index(RDI),the lowest oxygen saturatioo( LSpO2 ),the longest apnea time( Tmax),the percentage of recording time with oxygen saturation of 90％ or less(T90) between the patients and the controls.Daily Functioning,Social Interactions,Emotional Functioning,Symptoms,and total scores of SAQLI in patients with moderate to severe OSAHS were(3.88 ± 1.05),(4.48 ± 1.39),(4.76 ± 1.59),(2.98 ± 1.10),(3.94 ± 1.22),which were less than that of controls respectively.The ESS scoree of patients with moderate to severe OSAHS were higher than that of controls[ ( 13.98 ± 4.05 ) vs (5.78 ± 2.45) ],( P ＜ 0.01 ).ESS were related to the daily Functioning,social interactions,emotional functioning,symptoms,and total scores of SAQLI in patients with moderate to severe OSAHS,and the coecient of correlation were - 0.52,- 0.48,- 0.40,- 0.48 and - 0.44,respectively,and all p value were less than 0.01.Conclusion Patients with moderate to severe OSAHS have the EDS,which associate with the impairment of quality of life.The higher ESS may indicate the decrease of quality of life in patients with moderate to severe OSAHS.
