Diagnosis and treatment of 17 primary testicular lymphoma cases
10.3760/cma.j.issn.1673-4203.2012.06.006
- VernacularTitle:原发性睾丸淋巴瘤17例的诊治体会
- Author:
Yichen ZHU
;
Jin XIAO
;
Yuwen GUO
;
Haijun HOU
;
Ye TIAN
- Publication Type:Journal Article
- Keywords:
Primary testicular lymphoma;
Orchidectomy;
CHOP chemotherapy;
Prognosis
- From:
International Journal of Surgery
2012;39(6):377-379
- CountryChina
- Language:Chinese
-
Abstract:
Objective Concluding the clinical feature and prognosis of primary testicular lymphoma to improve the understanding of this disease.Methods During 1995 and 2010,17 cases of primary testicular lymphoma treated in Beijing Friendship Hospital of Capital Medical University were retrospectively analyzed of its clinical features,diagnosis,treatment and prognosis.Results Seventeen patients with a mean age of 68 years complained the testicular sohd mass as their first symptoms.The mean tumor diameter was 4.7 cm,and all patients underwent orchidectomy,and testicular non- Hodgkin's lymphoma was confirmed by pathologic examination.Fourteen cases were diffuse large B cell type and 3 cases were anaplastic large cell type.The clinical stage of all the patients was IE.Fourteen cases were followed up (3 cases were lost)with mean follow-up time of 37.8 months by outpatient interview and telephone,all patients were treated with CHOP chemotherapy,and some of them were combined with rituximab and preventive lowdose pelvic radiotherapy.Five cases died of other chronic medical complications,1 case with contralateral testicular metastasis received surgery again.There were 9 tumor free survival cases in total.Conclusion Primary testicular lymphoma is rare and more common in older men.Postoperative pathologic diagnosis is gold standard.The systemic treatment and individual therapy is the first choice for primary testicular lymphoma.
