Roles of cancer stem cells in tumor angiogenesis
10.3760/cma.j.issn.1673-422X.2012.06.001
- VernacularTitle:肿瘤干细胞在肿瘤血管生成中的作用
- Author:
Xiaoyue ZHANG
;
Weidong ZHANG
- Publication Type:Journal Article
- Keywords:
Neoplastic stem cells;
Neovascularization,pathologic
- From:
Journal of International Oncology
2012;39(6):403-405
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cells (CSC) play a crucial role in the tumor angiogenesis.Angiogenic factors and hypoxia mediate the process.CSC car differentiate into vascular endothelial cells and participate in the formation of vasculogenic mimicry,which may be one of the key factors in the initiation and progression of tumors.lndepth studies of the roles of CSC in tumor angiogenesis might help provide the basis for developing more effective therapeutic drug target.
