The clinical effect of Danhong injection in treatmant unstable angina and its effect on the endothelial function

VernacularTitle:丹红注射液治疗不稳定型心绞痛的疗效及对内皮功能的影响
Author: Zheming XU
Publication Type:Journal Article
Keywords: Danhong; Angina unstable; Endothelium,vascular
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(9):1337-1338
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical effect of Danhong injection to treat unstable angina and its effect on the endothelial function.Methods 100 cases with unstable angina were randomly divided into control group and treatment group,each group had 50 cases.All patients were hospitalized for routine treatment,the control group was given Isosorbide mononitrate and 5％ glucose solution or saline,while the treatment group was given Danhong injection and 5％ glucose solution or saline on the basis of the routine treatment.Results After treatment,the efficacy of ECG and angina in the treatment group were better than the control group( all P ＜ 0.05) ; the NO level of post-treatment was higher than pre-treatment,ET and CRP levels were lower than pre-treatment( all P ＜0.05 ) ;the NO level in the treatment group was higher than the control group,the ET and CRP levels were lower than the control group( all P ＜ 0.05 ).Conclusion Danhong injection for the treatment of patients with unstable angina could effectively relieve the angina and improve the endothelial function.