The significance of BNP for predicting prognosis in patients with early acute pulmonary embolism
10.3760/cma.j.issn.1671-0282.2012.06.019
- VernacularTitle:B型尿钠肽在急性肺栓塞早期病情评估的意义
- Author:
Zhizhong ZHANG
;
Guoxing WANG
;
Miaorong XIE
;
Lipei YANG
- Publication Type:Journal Article
- Keywords:
Acute pulmonary embolism;
Brain natriaretie peptide;
Troponin Ⅰ;
Fibrin degredation product;
D-Dimer;
C-reactive protein;
Right ventricular function;
Assessment;
Prognosis
- From:
Chinese Journal of Emergency Medicine
2012;21(6):638-641
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the role of BNP (B-type natriuretic peptide) in the early assessment of patients with acute pulmonary embolism (PE).MethodsEighty-six patients hospitalized in Beijing Friendship Hospital from November 2005 to June 2010 diagnosed as acute PE were studied retrospectively.The differences of BNP and other indicators and the relationship of BNP and right ventricular and right atrial pressure gradient value ( RV-RA PG) were compared between two groups divided by whether right ventricular dysfunction exists or not.imilarly,the differences of BNP and other indictors were compared between the two groups divided by complications exists or not.ResultsIn the right ventricular dysfunction group and control group,BNP was ( 1356.8 ±675.4) pg/ml and ( 103.8 ±51.4) pg/ml,respectively,and the differences are significant.BNP and RV-RA PG had a significant correlation (γ =0.824,P ＜0.01 ) by Linear correlation analysis.BNP had a reliable diagnostic power for right ventricular dysfunction ( AUC 0.907).In the group with complications and none -complication group,BNP value was ( 1356.8 ±675.4)pg/mlvs.(103.8 ±51.4) pg/ml,and pH value was (7.372 ±3.7) vs.(7.446 ±3.5),and the differences were all significant ( P ＜ 0.05 ). Conclusions BNP has important significance in early predicting the occurring,severity and prognosis of congestive heart failure caused by acute pulmonary embolism; pH of the early arterial blood gas has positive significance for early diagnose and treatment and predicting the severity and prognosis of patients suffering acute pulmonary embolism.
