Evaluation of dynamic changes of rabbit mulsle's restoration after damaging using acoustic radiation force impulse
10.3760/cma.j.issn.1004-4477.2012.06.024
- VernacularTitle:声脉冲辐射力成像技术评价家兔肌肉损伤后组织修复的动态变化
- Author:
Yan HU
;
Lei DONG
;
Xiaohong LIU
;
Yan ZHANG
;
Yuanyuan SUN
;
Yingluan WANG
;
Shuanglong WANG
;
Di LI
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Muscle injuries;
Acoustic radiation force impulse
- From:
Chinese Journal of Ultrasonography
2012;21(6):533-536
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the dynamic change of muscle tissue restoration after damaging at different observation time through acoustic radiation force impulse(ARFI).MethodsAccording to different observation time,16 healthy rabbits were randomly divided into four groups,including before injury,1 day after injury,7 day after injury,14 day after injury.A homemade gravity hammer was used to establish damage model of rabbit gastrocnemius,then applied ARFI to observe changes of virtual touch tissue quantification (VTQ) of gastrocnemius.All the rabbits were executed after measurement,then the pathological changes of muscle tissue were observed under microscope.Results The VTQ of damaged muscle group were significantly higher than that of nomal muscle group( P ＜0.01),and VTQ of 1 day,7day,14 day group after injuried had significant difference between two groups (P ＜ 0.01).Through pathological examination,normal musule fibers were continual and there were not swelling and bleeding.One days after injury,muscle fibers were fractured,swollen,bleeding and congestive.7 days after injury,large areas of muscle cells were necrotic,and amounts of calcium salt depositsed.14 days after injury,lots of fiber cells proliferated,and the deposits of calcium obviously reduced.The results of ultrasound elastography were consistent with these of pathological.ConclusionsARFI can direct,noninvasively evaluate the changes of muscle tissue restoration after different time of injury,and provide objective basis for diagnosis and treatment.
