Hepatocyte growth factor and its receptor in multiple myeloma

VernacularTitle:肝细胞生长因子及其受体在多发性骨髓瘤中的研究进展
Author: Chenglin HU ; Leihua FU ; Lin CHEN
Publication Type:Journal Article
Keywords: Hepatocyte growth factor; Multiple myeloma
From: Journal of International Oncology 2012;39(5):384-386
CountryChina
Language:Chinese
Abstract: Hepatocyte growth factor ( HGF),a multifunctional cytokine,plays a biological role through acting on the cell surface transmembrane receptor c-Met.The growth,invasion and metastasis of many tumors are associated with the abnormalities of HGF-c-Met signaling pathway.Studies found that HGF and its receptor c-Met have close relations with the occurrence,metastasis,invasion and prognosis of multiple myeloma.