Detection of myocardial perfusion defect with 320-row volume CT myocardial perfusion imaging
10.3760/cma.j.issn.1005-1201.2012.05.004
- VernacularTitle:320层容积CT心肌灌注成像对心肌灌注缺损的诊断价值
- Author:
Chuanchen ZHANG
;
Zhaoqi ZHANG
;
Qian WANG
;
Lei XU
;
Wei YU
;
Jian JIAO
;
Rui WANG
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Tomography,X-ray computed;
Myocardium;
Perfusion
- From:
Chinese Journal of Radiology
2012;46(5):396-400
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the feasibility of 320-row volume CT myocardial perfusion imaging (CT-MPI) in detecting myocardial perfusion defect.MethodsFourteen patients with positive single-positron emission computed tomography myocardial perfusion imaging (SPECT-MPI)findings underwent both rest and adenosine stress 320-row volume CT-MPI.Rest and stress CT perfusion images were analyzed by employing dedicated software in 320-row CT workstation.Both SPECT-MPI and CT-MPI were evaluated for fixed and reversible perfusion defects using a 16-segment model (apex was excluded).The sensitivity,specificity of 320-row volume CT-MPI in detecting myocardial perfusion defect were evaluated by taking SPECT-MPI as a reference standard.ResultsBoth rest and stress 320-row volume CT-MPI were successfully performed in all patients.Thirty nine segments with fixed or reversible perfusion defects in all patients were depicted by SPECT-MPI,while 34 perfusion defects in 12 patients were identified by CT-MPI.The sensitivity,specificity of 320-row volume CT-MPI for detection of perfusion defects were 87.2%(34/39),91.4% ( 169/185 ),respectively.Conclusion320-row volume CT-MPI has high sensitivity and specificity for detection of myocardial perfusion defects.