Clinical value of neuro-electrophysiological measure in Guillain-Barre syndrome
10.3760/cma.j.issh.1008-1372.2012.04.007
- VernacularTitle:神经电生理检测在吉兰-巴雷综合征中的临床价值
- Author:
Ying WANG
;
Wenhong HAN
;
Aibing REN
- Publication Type:Journal Article
- Keywords:
Guillain-barre syndrome/diagnosis/physiopathology;
Neurophysiology/methods;
Electrophysiology/methods
- From:
Journal of Chinese Physician
2012;14(4):458-460
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the characteristics of neuro-electrophysiology and clinical value in patients with Guillain-Barre syndrome.MethedsWe performed retrospective analysis of the clinical date of 46 patients with Guillain-Barre syndrome in our hospital.Hughes grades and neuro-electrophysiological measure including motor conduction velocity (MCV),complex muscle action potential (CMAP),sensory conduction velocity (SCV) and F wave,were investigated as the related factors with the prognosis of GBS.Results The rate of abnormal F wave was higher than the rate of abnormal MCV.The rate of abnormal SCV was lower than the rate of abnormal F wave and MCV( P <0.05).The prognosis of the acute inflammatory demyelinating polyneuropathy (AIDP) group was superior to the acute motor axonal neuropathy (AMAN) group,and there had significant difference( P <0.05).ConclusionsThe neuro-electrophysiological investigation is an important way to diagnose the GBS.F wave is a sensitive and specify index in the early diagnosis of GBS.The neuro-electrophysiological observation of MCV and CMAP may be served as cues for diagnosis,determination of the subtype and evaluation of the treatment effect in GBS.