Anti-tumor clinical research of mTOR inhibitor
10.3760/cma.j.issn.1673-422X.2012.05.012
- VernacularTitle:mTOR抑制剂抗肿瘤临床研究
- Author:
Xuyuan LI
;
Yingcheng LIN
- Publication Type:Journal Article
- Keywords:
Protein-serine-threonine kinases;
Drug therapy;
Neoplasms
- From:
Journal of International Oncology
2012;39(5):363-366
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,mTOR inhibitors such as temsirolimus and everolimus are considered to be effective as a new generation of anti-tumor agent.Their efficacies are proven by a number of clinical trials especially in the field of overcoming the drug resistance of tumor cells.But the optimal combination regimen of the mTOR inhibitors and other anti-tumor drugs is still to be validated.